| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Fernando Pacheco | CD Alaves | Spain | 57 | |
| 2 | Rui Silva | Granada CF | Portugal | 56 | |
| 3 | Marko Dmitrovic | Eibar | Serbia | 49 | |
| 4 | Jeremias Ledesma | Cadiz CF | Argentina | 48 | |
| 5 | Edgar Badia | Elche CF | Spain | 47 | |
| 6 | Jaume Domenech | Valencia | Spain | 44 | |
| 7 | Aitor Fernandez | Levante | Spain | 44 | |
| 8 | Unai Simon | Athletic Bilbao | Spain | 43 | |
| 9 | Sergio Asenjo | Villarreal | Spain | 43 | |
| 10 | Sergio Herrera | Osasuna | Spain | 40 | |
| 11 | Jordi Masip | Real Valladolid | Spain | 40 | |
| 12 | Alejandro Remiro | Real Sociedad | Spain | 39 | |
| 13 | Marc-Andre ter Stegen | Barcelona | Germany | 35 | |
| 14 | Alvaro Fernandez | Huesca SD | Spain | 34 | |
| 15 | Thibaut Courtois | Real Madrid | Belgium | 32 | |
| 16 | David Soria | Getafe | Spain | 32 | |
| 17 | Ruben Blanco | Celta Vigo | Spain | 30 | |
| 18 | Yassine Bounou | Sevilla | Morocco | 29 | |
| 19 | Ivan Villar | Celta Vigo | Spain | 27 | |
| 20 | Jan Oblak | Atletico Madrid | Slovenia | 27 |
GC = Goals conceded