| 4 | Salih Ozcan | Group Stage | UEFA Champions League 22/23 |
| 4 | Nico Schlotterbeck | Group Section | UEFA Champions League 23/24 |
| 4 | Emre Can | Group Section | UEFA Champions League 23/24 |
| 3 | Jeremy Toljan | Group Stage | UEFA Champions League 17/18 |
| 3 | Mats Hummels | Group Section | UEFA Champions League 23/24 |
| 3 | Ian Maatsen | Round of 16 | UEFA Champions League 23/24 |
| 3 | Sebastian Kehl | Group Stage | UEFA Champions League 13/14 |
| 3 | Robert Lewandowski | Group Stage | UEFA Champions League 13/14 |
| 3 | Kevin Grosskreutz | Group Stage | UEFA Champions League 12/13 |
| 3 | Marcel Schmelzer | Group Stage | UEFA Champions League 11/12 |
| 3 | Stefan Reuter | Semi-finals | UEFA Champions League 97/98 |
| 2 | Emre Can | Group Stage | UEFA Champions League 22/23 |
| 2 | Niklas Sule | Round of 16 | UEFA Champions League 22/23 |
| 2 | Jude Bellingham | Round of 16 | UEFA Champions League 22/23 |
| 2 | Emre Can | Round of 16 | UEFA Champions League 20/21 |
| 2 | Jude Bellingham | Quarter-finals | UEFA Champions League 20/21 |
| 2 | Erling Haaland | Round of 16 | UEFA Champions League 20/21 |
| 2 | Thorgan Hazard | Group Stage | UEFA Champions League 19/20 |
| 2 | Julian Weigl | Group Stage | UEFA Champions League 19/20 |
| 2 | Mats Hummels | Group Stage | UEFA Champions League 19/20 |
| 2 | Julian Weigl | Group Stage | UEFA Champions League 18/19 |
| 2 | Julian Weigl | Group Stage | UEFA Champions League 17/18 |
| 2 | Marcel Schmelzer | Group Stage | UEFA Champions League 16/17 |
| 2 | Sokratis Papastathopoulos | Group Stage | UEFA Champions League 16/17 |
| 2 | Raphael Guerreiro | Group Stage | UEFA Champions League 16/17 |
| 2 | Matthias Ginter | Group Stage | UEFA Champions League 16/17 |
| 2 | Julian Ryersen | Group Section | UEFA Champions League 23/24 |
| 2 | Marco Reus | Quarter-finals | UEFA Champions League 13/14 |
| 2 | Sven Bender | Group Stage | UEFA Champions League 13/14 |
| 2 | Kevin Grosskreutz | Quarter-finals | UEFA Champions League 13/14 |
| 2 | Ilkay Gundogan | Group Stage | UEFA Champions League 12/13 |
| 2 | Sven Bender | Quarter-finals | UEFA Champions League 12/13 |
| 2 | Stefan Reuter | Group Stage | UEFA Champions League 95/96 |
| 2 | Lars Ricken | Group Stage | UEFA Champions League 95/96 |
| 2 | Jurgen Kohler | Group Stage | UEFA Champions League 95/96 |
| 2 | Paulo Sousa | Quarter-finals | UEFA Champions League 96/97 |
| 2 | Jorg Heinrich | Group Stage | UEFA Champions League 96/97 |
| 2 | Matthias Sammer | Quarter-finals | UEFA Champions League 96/97 |
| 2 | Lars Ricken | Final | UEFA Champions League 96/97 |
| 2 | Jurgen Kohler | Group Stage | UEFA Champions League 96/97 |
| 2 | Michael Zorc | Group Stage | UEFA Champions League 96/97 |
| 2 | Heiko Herrlich | Group Stage | UEFA Champions League 96/97 |
| 2 | Julio Cesar | Semi-finals | UEFA Champions League 97/98 |
| 2 | Wolfgang Feiersinger | Quarter-finals | UEFA Champions League 97/98 |
| 2 | Steffen Freund | Semi-finals | UEFA Champions League 97/98 |
| 2 | Evanilson | Second Group Stage | UEFA Champions League 02/03 |
| 2 | Stefan Reuter | First Group Stage | UEFA Champions League 02/03 |
| 2 | Dede | First Group Stage | UEFA Champions League 02/03 |
| 2 | Torsten Frings | Second Group Stage | UEFA Champions League 02/03 |
| 2 | Dede | First Group Stage | UEFA Champions League 99/00 |
| 2 | Lars Ricken | First Group Stage | UEFA Champions League 99/00 |
| 2 | Evanilson | First Group Stage | UEFA Champions League 99/00 |
| 2 | Stefan Reuter | First Group Stage | UEFA Champions League 99/00 |
| 2 | Dede | First Group Stage | UEFA Champions League 01/02 |
| 1 | Thomas Meunier | Group Stage | UEFA Champions League 22/23 |
| 1 | Marius Wolf | Round of 16 | UEFA Champions League 22/23 |
| 1 | Mats Hummels | Group Stage | UEFA Champions League 22/23 |
| 1 | Karim Adeyemi | Round of 16 | UEFA Champions League 22/23 |
| 1 | Donyell Malen | Group Stage | UEFA Champions League 22/23 |
| 1 | Anthony Modeste | Group Stage | UEFA Champions League 22/23 |
