| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 21-Aug-2021 | draw |  Granada CF | 1-1 | away |
| 12-Sep-2021 | win |  Osasuna | 1-4 | away |
| 22-Sep-2021 | lose |  Sevilla | 3-1 | away |
| 25-Sep-2021 | draw |  Athletic Bilbao | 1-1 | home |
| 23-Oct-2021 | draw |  RCD Mallorca | 2-2 | home |
| 27-Oct-2021 | lose |  Real Betis | 4-1 | away |
| 07-Nov-2021 | draw |  Atletico Madrid | 3-3 | home |
| 05-Dec-2021 | win |  Celta Vigo | 1-2 | away |
| 20-Dec-2021 | win |  Levante | 3-4 | away |
| 08-Jan-2022 | lose |  Real Madrid | 4-1 | away |
| 19-Jan-2022 | draw | Sevilla | 1-1 | home |
| 13-Feb-2022 | lose |  CD Alaves | 2-1 | away |
| 20-Feb-2022 | lose |  Barcelona | 1-4 | home |
| 16-Apr-2022 | lose | Osasuna | 1-2 | home |
| 19-Apr-2022 | lose |  Villarreal | 2-0 | away |
| 10-May-2022 | lose | Real Betis | 0-3 | home |
Overall ( 3 wins,5 draw,8 lost )
Home ( 0 wins,4 draw,3 lost )
Away ( 3 wins,1 draw,5 lost )
OPP = Opposition,
FS = Final score.