| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 14-Aug-2021 | draw |  RCD Mallorca | 1-1 | away |
| 20-Aug-2021 | draw |  Cadiz CF | 1-1 | home |
| 28-Aug-2021 | lose |  Real Madrid | 0-1 | home |
| 19-Sep-2021 | draw |  Espanyol | 2-2 | home |
| 03-Oct-2021 | lose |  Villarreal | 2-0 | away |
| 31-Oct-2021 | lose |  Atletico Madrid | 3-0 | away |
| 07-Nov-2021 | lose |  Sevilla | 0-2 | home |
| 28-Nov-2021 | win |  Levante | 3-1 | home |
| 19-Dec-2021 | lose |  Athletic Bilbao | 3-2 | away |
| 02-Jan-2022 | lose |  Celta Vigo | 0-2 | home |
| 21-Jan-2022 | win | Espanyol | 1-4 | away |
| 06-Feb-2022 | lose | Villarreal | 0-2 | home |
| 27-Feb-2022 | lose | Sevilla | 2-1 | away |
| 06-Mar-2022 | lose | Atletico Madrid | 1-3 | home |
| 09-Apr-2022 | win | Cadiz CF | 1-2 | away |
| 19-Apr-2022 | lose |  Elche CF | 0-1 | home |
| 07-May-2022 | lose |  Barcelona | 1-2 | home |
Overall ( 3 wins,3 draw,11 lost )
Home ( 1 wins,2 draw,7 lost )
Away ( 2 wins,1 draw,4 lost )
OPP = Opposition,
FS = Final score.