| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 14-Aug-2021 | draw |  Levante | 1-1 | home |
| 12-Sep-2021 | lose |  Real Sociedad | 0-2 | home |
| 26-Sep-2021 | lose |  Rayo Vallecano | 3-1 | away |
| 18-Oct-2021 | lose |  Espanyol | 2-0 | away |
| 23-Oct-2021 | lose |  CD Alaves | 0-2 | home |
| 31-Oct-2021 | draw |  RCD Mallorca | 1-1 | home |
| 21-Nov-2021 | lose |  Getafe | 4-0 | away |
| 28-Nov-2021 | lose |  Atletico Madrid | 1-4 | home |
| 05-Dec-2021 | lose |  Elche CF | 3-1 | away |
| 03-Jan-2022 | lose |  Sevilla | 0-1 | home |
| 09-Jan-2022 | lose |  Osasuna | 2-0 | away |
| 18-Jan-2022 | draw | Espanyol | 2-2 | home |
| 19-Feb-2022 | draw | Getafe | 1-1 | home |
| 11-Mar-2022 | lose | Atletico Madrid | 2-1 | away |
| 21-Apr-2022 | lose |  Athletic Bilbao | 2-3 | home |
| 29-Apr-2022 | draw | Sevilla | 1-1 | away |
| 12-May-2022 | lose | Real Sociedad | 3-0 | away |
| 15-May-2022 | draw |  Real Madrid | 1-1 | home |
Overall ( 0 wins,6 draw,12 lost )
Home ( 0 wins,5 draw,5 lost )
Away ( 0 wins,1 draw,7 lost )
OPP = Opposition,
FS = Final score.