| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 21-Aug-2021 | win |  Genoa | 4-0 | home |
| 12-Sep-2021 | draw |  Sampdoria | 2-2 | away |
| 18-Sep-2021 | win |  Bologna | 6-1 | home |
| 25-Sep-2021 | draw |  Atalanta | 2-2 | home |
| 16-Oct-2021 | lose |  SS Lazio | 3-1 | away |
| 24-Oct-2021 | draw |  Juventus | 1-1 | home |
| 27-Oct-2021 | win |  Empoli | 0-2 | away |
| 31-Oct-2021 | win |  Udinese | 2-0 | home |
| 07-Nov-2021 | draw |  AC Milan | 1-1 | away |
| 27-Nov-2021 | win |  Venezia | 0-2 | away |
| 01-Dec-2021 | win | Spezia Calcio | 2-0 | home |
| 04-Dec-2021 | win |  AS Roma | 0-3 | away |
| 12-Dec-2021 | win |  Cagliari | 4-0 | home |
| 17-Dec-2021 | win | Salernitana | 0-5 | away |
| 22-Dec-2021 | win |  Torino | 1-0 | home |
| 09-Jan-2022 | win | SS Lazio | 2-1 | home |
| 05-Feb-2022 | lose | AC Milan | 1-2 | home |
| 04-Mar-2022 | win | Salernitana | 5-0 | home |
| 03-Apr-2022 | win | Juventus | 0-1 | away |
| 09-Apr-2022 | win | Hellas Verona | 2-0 | home |
| 15-Apr-2022 | win | Spezia Calcio | 1-3 | away |
| 23-Apr-2022 | win | AS Roma | 3-1 | home |
| 27-Apr-2022 | lose | Bologna | 2-1 | away |
| 01-May-2022 | win | Udinese | 1-2 | away |
| 15-May-2022 | win | Cagliari | 1-3 | away |
| 22-May-2022 | win | Sampdoria | 3-0 | home |
Overall ( 19 wins,4 draw,3 lost )
Home ( 11 wins,2 draw,1 lost )
Away ( 8 wins,2 draw,2 lost )
OPP = Opposition,
FS = Final score.