| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Samir Handanovic | 37 | 37 | 1 | - | - | - |
Nicolo Barella | 36 | 36 | 1 | - | 19 | 3 |
Edin Dzeko | 36 | 27 | 11 | 9 | 14 | 13 |
Marcelo Brozovic | 35 | 35 | - | - | 12 | 2 |
Ivan Perisic | 35 | 35 | 2 | - | 19 | 8 |
Milan Skriniar | 35 | 35 | 3 | - | - | 3 |
Lautaro Martinez | 35 | 28 | 8 | 7 | 24 | 21 |
Hakan Calhanoglu | 34 | 33 | 3 | 1 | 26 | 7 |
Denzel Dumfries | 34 | 22 | 16 | 12 | 8 | 5 |
Federico Dimarco | 32 | 13 | 25 | 19 | 7 | 2 |
Alessandro Bastoni | 31 | 29 | 3 | 2 | 16 | 1 |
Stefan de Vrij | 30 | 28 | 4 | 2 | 5 | - |
Arturo Vidal | 28 | 2 | 28 | 26 | 2 | 1 |
Alexis Sanchez | 27 | 7 | 26 | 20 | 5 | 5 |
Joaquin Correa | 26 | 12 | 14 | 14 | 12 | 6 |
Matteo Darmian | 24 | 17 | 16 | 7 | 9 | 2 |
Danilo D'Ambrosio | 20 | 9 | 28 | 11 | 1 | 1 |
Roberto Gagliardini | 18 | 6 | 29 | 12 | 5 | 2 |
Matias Vecino | 17 | 2 | 33 | 15 | 1 | 1 |
Stefano Sensi | 9 | 1 | 16 | 8 | 1 | - |
Robin Gosens | 7 | - | 11 | 7 | - | - |
Andrea Ranocchia | 6 | 3 | 33 | 3 | - | - |
Martin Satriano | 4 | - | 13 | 4 | - | - |
Felipe Caicedo | 3 | - | 13 | 3 | - | - |
Aleksandar Kolarov | 3 | - | 23 | 3 | - | - |
Ionut Radu | 1 | 1 | 37 | - | - | - |
Mattia Zanotti | 1 | - | 3 | 1 | - | - |
Alex Cordaz | - | - | 29 | - | - | - |
Lucien Agoume | - | - | 1 | - | - | - |
Fabio Cortinovis | - | - | 2 | - | - | - |
Franco Carboni | - | - | 5 | - | - | - |
Andrea Pinamonti | - | - | 1 | - | - | - |
Mattia Sangalli | - | - | 6 | - | - | - |
William Rovida | - | - | 1 | - | - | - |
Dennis Curatolo | - | - | 2 | - | - | - |
Cesare Casadei | - | - | 1 | - | - | - | 604 | 418 | 448 | 186 | 186 | 83 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .