| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Stephen Ireland | 35 | 34 | 1 | 1 | 3 | 9 |
Vincent Kompany | 34 | 34 | - | - | 4 | 1 |
Micah Richards | 34 | 33 | 2 | 1 | 8 | 1 |
Richard Dunne | 31 | 31 | - | - | 1 | 1 |
Robinho | 31 | 30 | 1 | 1 | 11 | 14 |
Pablo Zabaleta | 29 | 26 | 4 | 3 | 3 | 1 |
Blumer Elano | 28 | 21 | 14 | 7 | 12 | 6 |
Shaun Wright-Phillips | 27 | 27 | - | - | 2 | 5 |
Joe Hart | 23 | 23 | 15 | - | 1 | - |
Nedum Onuoha | 23 | 20 | 11 | 3 | 1 | 1 |
Felipe Caicedo | 17 | 10 | 13 | 7 | 9 | 4 |
Gelson Fernandes | 17 | 3 | 28 | 14 | 1 | 1 |
Nigel De Jong | 16 | 16 | - | - | 5 | - |
Wayne Bridge | 16 | 16 | - | - | 2 | - |
Ched Evans | 16 | 3 | 24 | 13 | 3 | 1 |
Daniel Sturridge | 16 | 3 | 17 | 13 | 2 | 4 |
Shay Given | 15 | 15 | - | - | - | - |
Javier Garrido | 13 | 11 | 22 | 2 | 2 | 1 |
Tal Ben Haim | 9 | 8 | 9 | 1 | - | - |
Jo | 9 | 6 | 11 | 3 | 3 | 1 |
Dietmar Hamann | 9 | 5 | 13 | 4 | 3 | - |
Martin Petrov | 9 | 4 | 6 | 5 | 3 | - |
Michael Ball | 8 | 8 | 5 | - | 1 | - |
Craig Bellamy | 8 | 7 | 1 | 1 | 1 | 2 |
Benjani Mwaruwari | 8 | 7 | 3 | 1 | 5 | 1 |
Darius Vassell | 8 | 6 | 10 | 2 | 3 | - |
Valeri Bojinov | 8 | 2 | 9 | 6 | 2 | 1 |
Kelvin Etuhu | 4 | 2 | 3 | 2 | 1 | - |
Vedran Corluka | 3 | 3 | - | - | - | 1 |
Michael Johnson | 3 | 3 | - | - | 1 | - |
Shaleum Logan | 1 | 1 | 1 | - | - | - |
Glauber | 1 | - | 14 | 1 | - | - |
Kasper Schmeichel | 1 | - | 23 | 1 | - | - |
Vladimir Weiss | 1 | - | 4 | 1 | - | - |
Adam Clayton | - | - | 1 | - | - | - |
Ryan McGivern | - | - | 1 | - | - | - | 511 | 418 | 266 | 93 | 93 | 56 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .