| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Shay Given | 35 | 35 | - | - | 1 | - |
Carlos Tevez | 35 | 32 | 3 | 3 | 11 | 23 |
Gareth Barry | 34 | 34 | 1 | - | 3 | 2 |
Nigel De Jong | 34 | 30 | 6 | 4 | 6 | - |
Craig Bellamy | 32 | 26 | 6 | 6 | 6 | 10 |
Kolo Toure | 31 | 31 | 3 | - | 3 | 1 |
Shaun Wright-Phillips | 30 | 19 | 16 | 11 | 7 | 4 |
Pablo Zabaleta | 27 | 23 | 11 | 4 | 1 | - |
Emmanuel Adebayor | 26 | 25 | 2 | 1 | 5 | 14 |
Vincent Kompany | 25 | 21 | 7 | 4 | 2 | 2 |
Wayne Bridge | 23 | 23 | 1 | - | 6 | - |
Micah Richards | 23 | 19 | 12 | 4 | 6 | 3 |
Stephen Ireland | 22 | 16 | 11 | 6 | 6 | 2 |
Roque Santa Cruz | 19 | 6 | 21 | 13 | 4 | 3 |
Joleon Lescott | 18 | 17 | 1 | 1 | - | 1 |
Adam Johnson | 16 | 14 | 2 | 2 | 10 | 1 |
Martin Petrov | 16 | 8 | 15 | 8 | 5 | 4 |
Patrick Vieira | 13 | 8 | 5 | 5 | 1 | 1 |
Silvinho | 10 | 6 | 21 | 4 | 3 | - |
Robinho | 10 | 6 | 6 | 4 | 7 | - |
Nedum Onuoha | 10 | 5 | 20 | 5 | - | 1 |
Javier Garrido | 9 | 7 | 8 | 2 | 2 | 1 |
Marton Fulop | 3 | 3 | - | - | - | - |
Dedryk Boyata | 3 | 1 | 9 | 2 | - | - |
Richard Dunne | 2 | 2 | - | - | - | - |
Benjani Mwaruwari | 2 | 1 | 2 | 1 | 1 | - |
Greg Cunningham | 2 | - | 2 | 2 | - | - |
Michael Johnson | 1 | - | 9 | 1 | - | - |
Abdisalam Ibrahim | 1 | - | 5 | 1 | - | - |
Alex Nimely | 1 | - | 1 | 1 | - | - |
Gunnar Nielsen | 1 | - | 7 | 1 | - | - |
Scott Kay | - | - | 1 | - | - | - |
Stuart Taylor | - | - | 31 | - | - | - |
Michael Ball | - | - | 1 | - | - | - |
Vladimir Weiss | - | - | 16 | - | - | - |
Javan Vidal | - | - | 3 | - | - | - | 514 | 418 | 265 | 96 | 96 | 73 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .