| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Juan Pablo | Sporting Gijon | Spain | 66 | |
| 2 | Andres Fernandez | Osasuna | Spain | 62 | |
| 3 | Roberto Gago | Real Zaragoza | Spain | 62 | |
| 4 | Claudio Bravo | Real Sociedad | Chile | 52 | |
| 5 | Gorka Iraizoz | Athletic Bilbao | Spain | 52 | |
| 6 | Miguel Angel Moya | Getafe | Spain | 51 | |
| 7 | Diego Lopez | Villarreal | Spain | 50 | |
| 8 | Gustavo Munua | Levante | Uruguay | 48 | |
| 9 | Dudu Aouate | RCD Mallorca | Israel | 48 | |
| 10 | Thibaut Courtois | Atletico Madrid | Belgium | 47 | |
| 11 | Willy Caballero | Malaga | Argentina | 39 | |
| 12 | Tono | Racing Santander | Spain | 38 | |
| 13 | Javier Varas | Sevilla | Spain | 36 | |
| 14 | Cristian Alvarez | Espanyol | Argentina | 34 | |
| 15 | Espinosa Casto | Real Betis | Spain | 31 | |
| 16 | Iker Casillas | Real Madrid | Spain | 31 | |
| 17 | Victor Valdes | Barcelona | Spain | 30 | |
| 18 | David Cobeno | Rayo Vallecano | Spain | 29 | |
| 19 | Roberto | Granada CF | Spain | 29 | |
| 20 | Joel Robles | Rayo Vallecano | Spain | 28 |
GC = Goals conceded