| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Andrea Consigli | Sassuolo | Italy | 38 | |
| 2 | Stefano Turati | Frosinone | Italy | 38 | |
| 3 | Ivan Provedel | SS Lazio | Italy | 36 | |
| 4 | Wladimiro Falcone | Lecce | Italy | 35 | |
| 5 | Mike Maignan | AC Milan | France | 34 | |
| 6 | Alex Meret | Napoli | Italy | 34 | |
| 7 | Wojciech Szczesny | Juventus | Poland | 32 | |
| 8 | Marco Carnesecchi | Atalanta | Italy | 29 | |
| 9 | Lukasz Skorupski | Bologna | Poland | 29 | |
| 10 | Josep Martinez | Genoa | Spain | 28 | |
| 11 | Michele Di Gregorio | Monza | Italy | 25 | |
| 12 | Lorenzo Montipo | Hellas Verona | Italy | 23 | |
| 13 | Simone Scuffet | Cagliari | Italy | 22 | |
| 14 | Rui Patricio | AS Roma | Portugal | 22 | |
| 15 | Yann Sommer | Internazionale | Switzerland | 21 | |
| 16 | Guillermo Ochoa | Salernitana | Mexico | 20 | |
| 17 | Etrit Berisha | Empoli | Albania | 19 | |
| 18 | Pietro Terracciano | Fiorentina | Italy | 19 | |
| 19 | Vanja Milinkovic-Savic | Torino | Serbia | 19 | |
| 20 | Benoit Costil | Salernitana | France | 18 |
GC = Goals conceded