| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 12-Sep-2021 | lose |  Udinese | 0-1 | home |
| 22-Sep-2021 | lose |  Juventus | 2-3 | home |
| 25-Sep-2021 | lose |  AC Milan | 1-2 | home |
| 03-Oct-2021 | lose |  Hellas Verona | 4-0 | away |
| 16-Oct-2021 | win | Salernitana | 2-1 | home |
| 22-Oct-2021 | lose |  Sampdoria | 2-1 | away |
| 31-Oct-2021 | lose |  Fiorentina | 3-0 | away |
| 28-Nov-2021 | lose |  Bologna | 0-1 | home |
| 01-Dec-2021 | lose |  Internazionale | 2-0 | away |
| 13-Dec-2021 | lose |  AS Roma | 2-0 | away |
| 06-Jan-2022 | lose | Hellas Verona | 1-2 | home |
| 17-Jan-2022 | win | AC Milan | 1-2 | away |
| 07-Feb-2022 | draw | Salernitana | 2-2 | away |
| 14-Feb-2022 | lose | Fiorentina | 1-2 | home |
| 27-Feb-2022 | lose | AS Roma | 0-1 | home |
| 06-Mar-2022 | lose | Juventus | 1-0 | away |
| 18-Mar-2022 | lose |  Sassuolo | 4-1 | away |
| 15-Apr-2022 | lose | Internazionale | 1-3 | home |
| 23-Apr-2022 | lose |  Torino | 2-1 | away |
| 08-May-2022 | lose |  Atalanta | 1-3 | home |
| 14-May-2022 | win | Udinese | 2-3 | away |
| 22-May-2022 | lose |  Napoli | 0-3 | home |
Overall ( 3 wins,1 draw,18 lost )
Home ( 1 wins,0 draw,10 lost )
Away ( 2 wins,1 draw,8 lost )
OPP = Opposition,
FS = Final score.