| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 29-Aug-2021 | lose |  AS Roma | 0-4 | home |
| 12-Sep-2021 | lose |  Torino | 4-0 | away |
| 18-Sep-2021 | lose |  Atalanta | 0-1 | home |
| 22-Sep-2021 | draw |  Hellas Verona | 2-2 | home |
| 26-Sep-2021 | lose |  Sassuolo | 1-0 | away |
| 23-Oct-2021 | lose |  Empoli | 2-4 | home |
| 26-Oct-2021 | win | Venezia | 1-2 | away |
| 31-Oct-2021 | lose |  Napoli | 0-1 | home |
| 07-Nov-2021 | lose |  SS Lazio | 3-0 | away |
| 21-Nov-2021 | lose |  Sampdoria | 0-2 | home |
| 26-Nov-2021 | draw |  Cagliari | 1-1 | away |
| 30-Nov-2021 | lose |  Juventus | 0-2 | home |
| 04-Dec-2021 | lose |  AC Milan | 2-0 | away |
| 11-Dec-2021 | lose |  Fiorentina | 4-0 | away |
| 17-Dec-2021 | lose |  Internazionale | 0-5 | home |
| 15-Jan-2022 | lose | SS Lazio | 0-3 | home |
| 23-Jan-2022 | lose | Napoli | 4-1 | away |
| 13-Feb-2022 | draw |  Genoa | 1-1 | away |
| 19-Feb-2022 | draw | AC Milan | 2-2 | home |
| 26-Feb-2022 | draw |  Bologna | 1-1 | home |
| 04-Mar-2022 | lose | Internazionale | 5-0 | away |
| 20-Mar-2022 | lose | Juventus | 2-0 | away |
| 02-Apr-2022 | lose | Torino | 0-1 | home |
| 14-May-2022 | draw | Empoli | 1-1 | away |
| 22-May-2022 | lose |  Udinese | 0-4 | home |
Overall ( 1 wins,6 draw,18 lost )
Home ( 0 wins,3 draw,10 lost )
Away ( 1 wins,3 draw,8 lost )
OPP = Opposition,
FS = Final score.