| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 23-Aug-2021 | lose |  AC Milan | 0-1 | home |
| 12-Sep-2021 | draw |  Internazionale | 2-2 | home |
| 23-Sep-2021 | lose |  Napoli | 0-4 | home |
| 26-Sep-2021 | lose |  Juventus | 3-2 | away |
| 03-Oct-2021 | draw |  Udinese | 3-3 | home |
| 17-Oct-2021 | lose |  Cagliari | 3-1 | away |
| 30-Oct-2021 | lose |  Torino | 3-0 | away |
| 07-Nov-2021 | lose |  Bologna | 1-2 | home |
| 27-Nov-2021 | win |  Hellas Verona | 3-1 | home |
| 05-Dec-2021 | lose |  SS Lazio | 1-3 | home |
| 22-Dec-2021 | draw |  AS Roma | 1-1 | away |
| 09-Jan-2022 | lose | Napoli | 1-0 | away |
| 23-Jan-2022 | lose | Spezia Calcio | 1-0 | away |
| 13-Feb-2022 | lose | AC Milan | 1-0 | away |
| 28-Feb-2022 | lose |  Atalanta | 4-0 | away |
| 05-Mar-2022 | lose | Udinese | 2-1 | away |
| 12-Mar-2022 | lose | Juventus | 1-3 | home |
| 03-Apr-2022 | lose | AS Roma | 0-1 | home |
| 11-Apr-2022 | lose | Bologna | 2-0 | away |
| 16-Apr-2022 | lose | Salernitana | 1-2 | home |
| 07-May-2022 | lose | SS Lazio | 2-0 | away |
| 22-May-2022 | lose | Internazionale | 3-0 | away |
Overall ( 1 wins,3 draw,18 lost )
Home ( 1 wins,2 draw,7 lost )
Away ( 0 wins,1 draw,11 lost )
OPP = Opposition,
FS = Final score.