| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 12-Sep-2021 | lose |  Valencia | 1-4 | home |
| 18-Sep-2021 | win |  CD Alaves | 0-2 | away |
| 26-Sep-2021 | win |  RCD Mallorca | 2-3 | away |
| 02-Oct-2021 | win |  Rayo Vallecano | 1-0 | home |
| 17-Oct-2021 | win |  Villarreal | 1-2 | away |
| 22-Oct-2021 | draw |  Granada CF | 1-1 | home |
| 29-Nov-2021 | draw |  Elche CF | 1-1 | home |
| 09-Jan-2022 | win |  Cadiz CF | 2-0 | home |
| 03-Jan-2022 | lose |  Athletic Bilbao | 1-3 | home |
| 23-Jan-2022 | win | Granada CF | 0-2 | away |
| 12-Feb-2022 | win | Rayo Vallecano | 0-3 | away |
| 05-Mar-2022 | win | Villarreal | 1-0 | home |
| 19-Mar-2022 | win |  Levante | 3-1 | home |
| 10-Apr-2022 | win | CD Alaves | 1-0 | home |
| 16-Apr-2022 | win | Valencia | 1-2 | away |
| 01-May-2022 | draw | Elche CF | 1-1 | away |
| 08-May-2022 | draw |  Espanyol | 1-1 | away |
| 11-May-2022 | draw |  Getafe | 1-1 | home |
Overall ( 11 wins,5 draw,2 lost )
Home ( 5 wins,3 draw,2 lost )
Away ( 6 wins,2 draw,0 lost )
OPP = Opposition,
FS = Final score.