| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 29-Aug-2021 | draw |  Atletico Madrid | 2-2 | away |
| 22-Sep-2021 | win |  Elche CF | 4-1 | home |
| 03-Oct-2021 | win |  Real Betis | 2-0 | home |
| 07-Nov-2021 | win |  Getafe | 1-0 | home |
| 20-Nov-2021 | draw |  Celta Vigo | 1-1 | away |
| 12-Dec-2021 | win |  Rayo Vallecano | 2-0 | home |
| 21-Dec-2021 | win |  CD Alaves | 5-2 | home |
| 03-Jan-2022 | win |  Levante | 5-0 | home |
| 22-Jan-2022 | win |  RCD Mallorca | 3-0 | home |
| 06-Feb-2022 | win | Real Betis | 0-2 | away |
| 19-Feb-2022 | win |  Granada CF | 1-4 | away |
| 27-Feb-2022 | win |  Espanyol | 5-1 | home |
| 12-Mar-2022 | win | Celta Vigo | 1-0 | home |
| 16-Apr-2022 | win | Getafe | 1-2 | away |
| 19-Apr-2022 | win |  Valencia | 2-0 | home |
| 08-May-2022 | draw |  Sevilla | 1-1 | home |
| 12-May-2022 | win | Rayo Vallecano | 1-5 | away |
| 15-May-2022 | lose |  Real Sociedad | 1-2 | home |
| 22-May-2022 | win |  Barcelona | 0-2 | away |
Overall ( 15 wins,3 draw,1 lost )
Home ( 10 wins,1 draw,1 lost )
Away ( 5 wins,2 draw,0 lost )
OPP = Opposition,
FS = Final score.