| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 11-Sep-2021 | lose |  Venezia | 1-2 | home |
| 19-Sep-2021 | lose |  Sampdoria | 0-3 | home |
| 03-Oct-2021 | lose |  AS Roma | 2-0 | away |
| 17-Oct-2021 | lose |  Atalanta | 1-4 | home |
| 27-Oct-2021 | lose |  Internazionale | 0-2 | home |
| 31-Oct-2021 | win |  Sassuolo | 1-2 | away |
| 05-Nov-2021 | draw |  Genoa | 2-2 | home |
| 22-Nov-2021 | lose | Hellas Verona | 2-1 | away |
| 27-Nov-2021 | win |  Fiorentina | 2-1 | home |
| 02-Dec-2021 | draw |  Torino | 2-2 | away |
| 06-Dec-2021 | win |  Udinese | 3-1 | home |
| 19-Dec-2021 | draw | Spezia Calcio | 1-1 | away |
| 22-Dec-2021 | lose |  AC Milan | 2-4 | home |
| 09-Jan-2022 | lose | Sassuolo | 1-5 | home |
| 23-Jan-2022 | lose | AS Roma | 2-4 | home |
| 19-Feb-2022 | lose | Sampdoria | 2-0 | away |
| 26-Feb-2022 | lose |  Juventus | 2-3 | home |
| 12-Mar-2022 | lose | AC Milan | 1-0 | away |
| 03-Apr-2022 | lose | Fiorentina | 1-0 | away |
| 16-Apr-2022 | lose | Udinese | 4-1 | away |
| 24-Apr-2022 | win |  Napoli | 3-2 | home |
Overall ( 4 wins,3 draw,14 lost )
Home ( 3 wins,1 draw,8 lost )
Away ( 1 wins,2 draw,6 lost )
OPP = Opposition,
FS = Final score.