| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 12-Sep-2021 | lose |  Real Madrid | 5-2 | away |
| 21-Sep-2021 | win |  Levante | 0-2 | away |
| 27-Sep-2021 | win |  Granada CF | 1-0 | home |
| 25-Oct-2021 | win |  Getafe | 0-3 | away |
| 27-Nov-2021 | win |  CD Alaves | 1-2 | away |
| 05-Dec-2021 | lose |  Valencia | 1-2 | home |
| 17-Dec-2021 | win |  Espanyol | 3-1 | home |
| 02-Jan-2022 | win |  Real Betis | 0-2 | away |
| 19-Jan-2022 | win |  Osasuna | 2-0 | home |
| 22-Jan-2022 | draw |  Sevilla | 2-2 | away |
| 05-Feb-2022 | win |  Rayo Vallecano | 2-0 | home |
| 21-Feb-2022 | draw | Levante | 1-1 | home |
| 06-Mar-2022 | win |  RCD Mallorca | 4-3 | home |
| 17-Apr-2022 | win |  Athletic Bilbao | 0-2 | away |
| 01-May-2022 | draw | Granada CF | 1-1 | away |
| 07-May-2022 | win | CD Alaves | 4-0 | home |
| 15-May-2022 | win |  Elche CF | 1-0 | home |
Overall ( 12 wins,3 draw,2 lost )
Home ( 7 wins,1 draw,1 lost )
Away ( 5 wins,2 draw,1 lost )
OPP = Opposition,
FS = Final score.