| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 15-Aug-2021 | lose |  1. FSV Mainz 05 | 1-0 | away |
| 29-Aug-2021 | lose |  VfL Wolfsburg | 1-0 | away |
| 11-Sep-2021 | lose |  Bayern Munich | 1-4 | home |
| 18-Sep-2021 | draw |  1. FC Koln | 1-1 | away |
| 23-Oct-2021 | win |  SpVgg Greuther Furth | 4-1 | home |
| 20-Nov-2021 | lose |  TSG 1899 Hoffenheim | 2-0 | away |
| 28-Nov-2021 | lose |  Bayer Leverkusen | 1-3 | home |
| 03-Dec-2021 | lose | 1. FC Union Berlin | 2-1 | away |
| 18-Dec-2021 | lose | Arminia Bielefeld | 0-2 | home |
| 05-Feb-2022 | lose | Bayern Munich | 3-2 | away |
| 05-Mar-2022 | draw |  SC Freiburg | 1-1 | home |
| 13-Mar-2022 | win | SpVgg Greuther Furth | 1-6 | away |
| 02-May-2022 | lose |  Borussia M'gladbach | 3-1 | away |
| 14-May-2022 | draw | Arminia Bielefeld | 1-1 | away |
Overall ( 2 wins,3 draw,9 lost )
Home ( 1 wins,1 draw,3 lost )
Away ( 1 wins,2 draw,6 lost )
OPP = Opposition,
FS = Final score.